Biochemistry and Molecular Biology

Volume 9, Issue 1, March 2024

  • Research Article

    Evaluating Gene Expression and Signaling Activities in Lipopolysaccharide Induced Human Peripheral Blood Mononuclear Cells

    Kristin Zindel, Sarah Whiteman, Kurstin Wiewel, Anne Turner, Meghan McGivern, Suzanne Stapleton, Marti Jett, Chanaka Mendis*

    Issue: Volume 9, Issue 1, April 2024
    Pages: 1-6
    Received: Nov. 28, 2023
    Accepted: Dec. 23, 2023
    Published: Jan. 08, 2024
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    Abstract: Lipopolysaccharide (LPS) is an endotoxin that induces the secretion of pro-inflammatory cytokines in multiple cell types that ultimately could lead to septic shock in humans. This study is aimed at identifying a set of functionally relevant genes induced by LPS and evaluating the effect of signal transduction pathway inter-connector, cJun N-termina... Show More
  • Research Article

    Effect of Biochar Application on Early Germination Rate of Water Melon Seeds

    Opara Ifeoma Juliet, Ukoha Pius Oziri, Obasi Nnamdi Lawrence, Ekere Nwachukwu

    Issue: Volume 9, Issue 1, April 2024
    Pages: 7-16
    Received: Aug. 14, 2023
    Accepted: Sep. 06, 2023
    Published: Jan. 08, 2024
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    Abstract: The effect of applying biochar produced at three temperatures (450-550°C) on the growth rate of watermelon seedlings is examined in this study. According to the proximate analysis, the fixed carbon content of groundnut shell biochar increases between 69.41 and 75.78% as the temperature rises. While the yield decreased as the temperature increased, ... Show More
  • Research Article

    Evaluation of Rhizobia Strain of Soybean (G. max) for Symbiotic Performance Grown in Acid-Prone Areas

    Mamo Bekele*, Getachew Yilma

    Issue: Volume 9, Issue 1, April 2024
    Pages: 17-21
    Received: Dec. 08, 2023
    Accepted: Dec. 27, 2023
    Published: Jan. 11, 2024
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    Abstract: The development of bio fertilizer for the legume crop is the crucial activity in the enhancement of sustainable agriculture to fulfill the human welfare. This research was focused on such aims through justifying the objective of evaluate the rhizobia isolate naturally associated with soybean obtained from acidic environment during the cropping seas... Show More
  • Research Article

    Highly Active Antiretroviral Treatment of HIV-1 Patients, Molecular Evaluation of AZT+3TC+EFV Regim

    Babacar Faye*, Bineta Ndiaye, Cheikh Madické Ndiaye, Mame Diarra Bousso Lam, Ismaïl Barkiré, Micailou Magassouba, Cathy Cissé, Aissatou Ngom, Alioune Dièye

    Issue: Volume 9, Issue 1, April 2024
    Pages: 23-29
    Received: Dec. 19, 2023
    Accepted: Jan. 06, 2024
    Published: Jan. 18, 2024
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    Abstract: Background: Antiretroviral therapy (ART) is an effective way to reduce the risk of HIV transmission. Several studies have demonstrated a reduction of sexual transmission of HIV in people on ART treatment and the main objective of antiretroviral treatment is to avoid the increase of, morbidity and mortality associated to AIDS. Furthermore, the 2030 ... Show More